1.Bonday, Z.Q., Dhanasekaran, S., Rangajaran, P.N.& Padmanaban, G.(2000)
Import of host d-aminolevulinate dehydratase into the malaria parasite: identification of a novel
drug target.Nature Med. 6, 898-903. NatMed
2.
Harry A. Dailey,(1997) Enzymes of heme biosynthesisJBIC 2 4, 411-417 Bmol (No Pubmed entry available)
3.James G. Wetmur,(1994) Influence of the Common Human delta-Aminolevulinate Dehydratase Polymorphism on
Lead Body Burden Molecular Mechanisms of Metal Toxicity and Carcinogenicity
Environmental Health Perspectives 102, Supplement 3,September CDC
4.Fleming DE, Chettle DR, Wetmur JG, et al.(1998) Effect of the delta-aminolevulinate dehydratase polymorphism on
the accumulation of lead in bone and blood in lead smelter workers
Environ Res;77(1):49-61. CDC
5. Pratima Srivastava, V. C. Pandey,(1998), Heme Synthesizing Enzymes of Plasmodium knowlesi:
A Simian Malarial Parasite
Exp Parasitol Jan;88(1):60-3 JSC
6.Erskine PT, Senior N, Awan S, Lambert R, Lewis G, Tickle IJ, Sarwar M, Spencer P, Thomas P,
Warren MJ, Shoolingin-Jordan PM, Wood SP, Cooper JB, (1997) X-ray structure of 5-aminolaevulinate dehydratase,
a hybrid aldolase.
Nat Struct Biol. Dec;4 Pubmed
7. Erskine PT, Newbold R, Roper J, Coker A, Warren MJ, Shoolingin-Jordan PM,
Wood SP,Cooper JB, (1999) The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid
Protein Sci. Jun:8. Pubmed
8. Frankenberg N, Erskine PT, Cooper JB, Shoolingin-Jordan PM, Jahn D, Heinz DW, (1999)
High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase.
J Mol Biol. Jun 11 Pubmed
9. Erskine PT, Senior N, Maignan S, Cooper J, Lambert R, Lewis G, Spencer P, Awan S Warren M, Tickle IJ,
Thomas P, Wood SP, Shoolingin-Jordan (1997) Crystallization of 5-aminolaevulinic acid dehydratase from
Escherichia coli and Saccharomyces cerevisiae and preliminary X-ray characterization of the crystals. ,
Protein Sci. Aug;6 Pubmed
10. Erskine PT, Coates L, Newbold R, Brindley AA, Stauffer F, Wood SP, Warren MJ, Cooper JB, Shoolingin-Jordan
PM, (2001) The X-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with two diacid inhibitors.
Neier R. FEBS Lett. Aug 17 Pubmed
11. Senior NM, Brocklehurst K, Cooper JB, Wood SP, Erskine P, Shoolingin-Jordan PM, Thomas PG, Warren MJ,
(1996) Comparative studies on the 5-aminolaevulinic acid dehydratases from Pisum sativum, Escherichia coli and
S.cerevisiae Biochem J. Dec 1 Pubmed
12. Erskine PT, Newbold R, Brindley AA, Wood SP, Shoolingin-Jordan PM, Warren MJ, Cooper, (2001)
The x-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with substrate and three inhibitors.
J Mol Biol. Sep 7 Pubmed
13. Erskine PT, Senior N, Maignan S, Cooper J, Lambert R, Lewis G, Spencer P, Awan S, Warren M, Tickle IJ,
Thomas P, Wood SP, Shoolingin-Jordan PM, (1997)Crystallization of 5-aminolaevulinic acid dehydratase from
Escherichia coli and Saccharomyces cerevisiae and preliminary X-ray characterization of the crystals.
Protein Sci. Aug;6 Pubmed
14. Erskine PT, Norton E, Cooper JB, Lambert R, Coker A, Lewis G, Spencer P, Sarwar M, Wood SP, Warren
MJ,Shoolingan-Jordan PM. X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed
with the inhibitor levulinic acid at 2.0 A resolution.BiochemistryApr Pubmed
15. Samir N.Kelada, Erin Shelton, Rachel B.Kaufman and Muin J.Khoury Delta Aminolevulinic acid dehydratase
genotype and Lead toxicity: June 2001, A huge review American Journal of Epidemology CDC
16. Ellen K.Jaffe, Jukka Kervinen, Jacob martins, Nicole Frankenubrg, Erica Yoon,
Matthew Sazinsky and jian Li: How enzymes work FCCC17. IC and Darwinian Pathways - ARN Intelligent Design Discussion
Author-Art member ARN
18. Richard E Frye, Thomas G DeLoughery,Porphyria: Acute
eMedicine Journal Emed
19. Featured products
DTT Pubmed
20. Eileen K. Jaffe The porphyrobilinogen synthase family of metalloenzymes--Research interests of Eileen.K.Jaffe
21. F. A. Beber, J. Wollmeister, M. J. K. Brigo, M. C. J. Silva, C. N. Pereira and J. B. T.Rocha, Departamento de
Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil
d-Aminolevulinate Dehydratase Inhibition by Ascorbic Acid is Mediated by an Oxidation System Existing in the
Hepatic Supernatant HH
22.Kervinen J, Jaffe EK, Stauffer F, Neier R, Wlodawer A, Zdanov A.(2001)
Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that
shows dramatic species selectivity.BiochemistryJul 27;40(28):8227-36 Pubmed
23. Eileen K. Jaffe(1995) Porphobilinogen synthase, The First Source of Heme's Asymmetry
(No Pubmed entry found) FCCC
24. Jukka Kervinen, Eileen K. Jaffe, FrĂdĂric Stauffer, Reinhard Neier, Alexander Wlodawer, and Alexander
Zdanovx (2001) Mechanistic Basis for Suicide Inactivation of Porphobilinogen Synthase by 4,7-Dioxosebacic Acid, an
inhibitor that shows dramatic species selectivity Biochemistry,40(28),8227-8236. ACS
25.Kaido M, Fukada K, Moriya M, Abe K, Sakoda S, Kondo M, Yanagihara T.(2001)
Porphyria with double errors in the heme biosynthetic pathway.J Neurol Apr;248(4):328-9 JNeurol
26.Maruno M, Furuyama K, Akagi R, Horie Y, Meguro K, Garbaczewski L, Chiorazzi N, Doss MO, Hassoun A,
Mercelis R, Verstraeten L, Harper P, Floderus Y, Thunell S, Sassa S.(2001)
Highly heterogeneous nature of delta-aminolevulinate dehydratase (ALAD) deficiencies in ALAD porphyria.
Blood May 15;97(10):2972-8 Pubmed
27.Gibson SL, Havens JJ, Metz L, Hilf R.(2001) Is delta-aminolevulinic acid dehydratase rate limiting in heme
biosynthesis following exposure of cells to delta-aminolevulinic acid?
Photochem Photobiol Mar;73(3):312-7 Pubmed
28.Farina M, Folmer V, Bolzan RC, Andrade LH, Zeni G, Braga AL, Rocha JB.(2001)
Selenoxides inhibit delta-aminolevulinic acid dehydratase.Toxicol Lett Feb 3;119(1):27-37Pubmed
29.Coto-Montes A, Boga JA, Tomas-Zapico C, Rodriguez-Colunga MJ, Martinez-Fraga J, Tolivia-Cadrecha D,
Menendez G, Hardeland R, Tolivia D.(2001) Porphyric enzymes in hamster Harderian gland, a model of damage by
porphyrins and their precursors. A chronobiological study on the role of sex differences.
Chem Biol Interact Apr 16;134(2):135-49 Pubmed
30.Goulart EC, Pereira CA, Garcia RC, Giacomelli MB, Rodrigues AL.(2001)
Effects of lead and/or zinc exposure during the second stage of rapid postnatal brain growth on delta-aminolevulinate
dehydratase and negative geotaxis of suckling rats. Braz J Med Biol Res Jun;34(6):785-90 Pubmed